1. Quantitative Measurement of Tear Film Dynamics with Optical Coherence Tomography and Statistical Decision Theory

    Quantitative Measurement of Tear Film Dynamics with Optical Coherence Tomography and Statistical Decision Theory

    Currently, there are about 40 to 60 million Americans suffering from Dry Eye Syndrome (DES); this serious public health problem will worsen with the explosive aging population created by baby boomers, where DES has a high incidence. However, the therapeutics for DES are elusive because our understanding of DES is so elementary, especially the correlation between symptoms and the diagnosis. Unfortunately, a quantitative diagnosis, which is the prerequisite to advance the management of DES, is yet to be realized. We are seeking the next breakthrough in DES management by providing a quantitative diagnosis, with the combination of optical coherence tomography ...

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