University of Cyprus receives a grant of 163,780 Euro ($208,844) enhancing the resolution of Optical Coherence Tomography.
The University of Cyprus is the recipient of a 163,780 Euro ($208,844) grant from the Research Promotion Foundation of Cyprus, titled “Novel Technology Development for Super-Resolution Optical Coherence Tomography.” The program is a two-year program, starting in Sept. 2012 and ending in Aug. 2014. The principle investigator is Prof. Costas Pitris with post-doctoral associate Evgenia Bousi. A brief description of the project is given below.
The main objective of this project is to develop novel techniques which will lead to significantly improved OCT resolution. To achieve this goal a combination of both optical enhancements and post-processing will be employed. Properly designed diffractive elements that shape the Point Spread Function (PSF) of the imaging system, such as pupil-plane phase masks and binary filters, can completely reshape the spatial light intensity distribution. Higher resolution in the axial or transverse directions and, even, three-dimensional super-resolution is, thus, possible. Moreover some novel off-line numerical processing methods will be developed to remove some of the adverse effects of the proposed filters, e.g. sidelobes, and, at the same time further improve the axial and lateral resolution. The project will include both simulations and experimental evaluation of the above techniques. Finally, the combination of these techniques will be tested in a clinical setting to evaluate their true potential as a diagnostic tool for the identification of cancerous lesions. The results of the imaging and the analysis will be compared to histopathology and are expected to confirm the efficacy of the proposed technology for the non-invasive identification of cancer. The proposed project will result in new technology which will significantly improve the resolution of OCT images revealing sub-cellular level features. When these results are incorporated into clinical OCT systems, they will offer unprecedented imaging resolution thus increasing the effectiveness of OCT as a tool for the diagnosis of very early cancer and other disease processes. More information will appear on the projects website HERE.
The proposed research will be performed in the Biomedical Imaging and Applied Optics (BIAO) Laboratory of the University of Cyprus. The partners are the National Technical University of Athens (NTUA) through the Institute of Communication and Computer Systems (ICCS) and the Nicosia General Hospital (NGH).