1. Transcatheter renal sympathetic ablation for resistant hypertension: in vivo insights in humans from optical coherence tomography

    Transcatheter renal sympathetic ablation for resistant hypertension: in vivo insights in humans from optical coherence tomography

    Hypertension represents a major health problem, with resistant hypertension being defined as uncontrolled blood pressure despite the use of optimal doses of ≥3 antihypertensive agents . Patients with resistant hypertension often have an increased renal sympathetic nerve activity, and building upon the historical experience with surgical renal sympathetic denervation, transcatheter radiofrequency ablation has been recently proposed . The safety profile of this novel technique appears satisfactory , but there is still limited insight on how such denervation works. We hereby report on two patients who underwent transcatheter ablation at our center, in whom optical coherence tomography (OCT) was concomitantly performed to provide more ...

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