1. Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography

    Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography

    We here develop a method to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT). Tissue is modelled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. Under the first-order Born approximation, the forward model is established for ISOCT. By measuring optical quantities of tissue including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio of scattering coefficient μ s , and the backscattering coefficient μ b , we are able to inversely deduce the RI correlation function and image the full ...

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