Automated segmentation of the choroid from clinical SD-OCT
Purpose: To develop and evaluate a fully automated three-dimensional method for segmentation of the choroidal vessels, quantification of choroidal vasculature thickness and choriocapillaris-equivalent thickness of the macula, and evaluate repeat variability in normal subjects using standard clinically available SD-OCT. Methods: normal subjects (24) were imaged twice, using clinically available, 3D spectral-domain optical coherence tomography (Cirrus, Carl-Zeiss, Dublin, CA). A novel, fully-automated three-dimensional method was used to segment and visualize the choroidal vasculature in macular scans. Local choroidal vasculature and choriocapillaris-equivalent thicknesses were determined. Reproducibility on repeat imaging was analyzed using overlapping rates, Dice coefficient, and Root Mean Square Coefficient ...
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