Wide-Field Spectral-Domain Optical Coherence Tomography in Patients and Carriers of X-linked Retinoschisis
Purpose: To evaluate macular and extramacular retinal anatomy in patients and carriers of X-linked retinoschisis (XLRS) using a wide-field spectral-domain optical coherence tomography (SD-OCT) imaging technique.Design: Case series.Participants: Six XLRS-affected male subjects and 3 XLRS female carriers.Methods: The subjects prospectively underwent XLRS DNA genotyping and comprehensive ophthalmic examination, including visual acuity, 30-2 Humphrey visual field, fundus photography, and wide-field SD-OCT, a montage technique to generate SD-OCT images spanning approximately 50 degrees horizontally and 35 degrees vertically of the posterior pole.Main Outcome Measures: Distribution and location of schisis cavities.Results: Among male subjects affected by XLRS, asymmetric ...
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