1. Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

    Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

    Angle-resolved optical scattering properties of ovarian tissue, on different optical coherence tomography (OCT) imaging planes, were quantitatively measured by fitting the compounded OCT A-lines into a single scattering model. Higher cross correlation value of angle-resolved scattering coefficients between different OCT imaging planes was found in normal ovaries than was present in malignant ovaries. The mean cross correlation coefficient (MCC) was introduced in this pilot study to characterize and differentiate normal, n=6 , and malignant, n=4 , ovaries. A specificity of 100 percent and a sensitivity of 100 percent were achieved by setting MCC threshold at 0.6. Collagen properties, within ...

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