1. 'En face' OCT imaging of the IS/OS junction line in Type 2 Idiopathic Macular Telangiectasia

    'En face' OCT imaging of the IS/OS junction line in Type 2 Idiopathic Macular Telangiectasia

    Purpose: To investigate abnormalities of the photoreceptor inner/outer segment (IS/OS) junction layer viewed 'en face' and their functional correlates in Type 2 Idiopathic Macular Telangiectasia (type 2 MacTel). Methods: Segmentation and 'en face' imaging of the IS/OS lines in spectral domain optical coherence tomographic (SD-OCT) volumes were performed manually. Mesopic retinal sensitivity thresholds were determined using a Nidek MP1 microperimeter. 'En face' SD-OCT images and microperimetric data were superimposed over images of the fundus. Retinal structure and characteristics of type 2 MacTel were analyzed, associations of structural changes with function were investigated. Results: Forty-nine eyes of 28 ...

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