1. Specific Spectral Domain Optical Coherence Tomographic Findings of Oguchi Disease

    Specific Spectral Domain Optical Coherence Tomographic Findings of Oguchi Disease

    PurposeTo report specific spectral domain OCT findings of Oguchi disease diagnosed with fundoscopic examination and electrophysiological study. Case summaryA 14-year-old patient visited our clinic with a complaint of night blindness for ten years. Fundoscopic examination showed a golden-yellow fundus reflex. After three hours of dark adaptation, the fundus color returned to normal (Mizuo-Nakamura phenomenon). In full-field ERG, rod b-wave was not detectable. The a-wave amplitude in maximal combined response increased after three hours of dark adaptation, although the b-wave amplitude was similar to the amplitude before dark adaptation, demonstrating a negative waveform. In the spectral domain OCT images of the ...

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