1. Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema

    Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema

    Purpose:Hyperreflective foci (HF) are observable within the neurosensory retina in diabetic macular edema (DME) using spectral domain optical coherence tomography (SD-OCT). The HF behaviour was evaluated during Anti-VEGF therapy in DME. Methods: Fifty-one patients (mean age: 67 years) underwent SD-OCT (Heidelberg engineering, Germany) before and one month after one Anti-VEGF injection (Ranibizumab: n=30; Bevacizumab: n=21). The amount of HFs were semi-quantitatively counted, assigned to 3 groups (A: SDPs n=1-10; B: n=11-20; C: n>20) and correlated to the course of visual acuity and foveal thickness (paired t-test). Additionally the baseline HbA1c was categorized and correlated ...

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