1. Theoretical, Experimental, and Optical Coherence Tomography (OCT) Studies of Graft Apposition and Adhesion in Descemets Stripping Automated Endothelial Keratoplasty (DSAEK)

    Theoretical, Experimental, and Optical Coherence Tomography (OCT) Studies of Graft Apposition and Adhesion in Descemets Stripping Automated Endothelial Keratoplasty (DSAEK)

    Purpose. To investigate the effects of adhesion promoting surgical adjuncts in Descemets stripping automated endothelial keratoplasty (DSAEK). The effects of air-fill pressure, duration, use of venting incisions and stromal roughening on fluid dispersion, and donor adhesion strength were examined in theoretical, optical coherence tomography (OCT), and strain gauge models of DSAEK. Methods. OCT analysis: DSAEK modeled using a microkeratome prepared lenticule inserted under a “recipient” corneo-scleral rim mounted on an artificial anterior chamber. Pressure of 18 mm Hg (n = 6) or 60 mm Hg (n = 6) was applied. The area of interface fluid was measured sequentially. The area of interface ...

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