1. How Do OCT and IVUS Compare to Histology in Coronary Atherosclerosis and Stenting?

    How Do OCT and IVUS Compare to Histology in Coronary Atherosclerosis and Stenting?

    Abstract  Recent advances in intra-coronary imaging modalities have enabled us to evaluate precise plaque morphologies and vascular response to coronary stents in vivo. Superior resolution of optical coherence tomography (OCT) allows the measurement of fibrous cap thickness and detection of macrophage accumulation, both of which are critical to identify vulnerable plaques. Poor penetration of OCT however limits the assessment of plaque volume and vessel remodeling, while intravascular ultrasound (IVUS) is capable of evaluating these parameters. Caution must be exercised when interpreting IVUS-based tissue characterization because this technology lacks sufficient resolution to evaluate plaque composition. In stented arteries, OCT has the ...

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