1. Differentiation between normal renal tissue and renal tumours using functional optical coherence tomography: a phase I in vivo human study

    Differentiation between normal renal tissue and renal tumours using functional optical coherence tomography: a phase I in vivo human study

    Optical Coherence Tomography (OCT) was developed in the early 1990s for ophthalmological application and is currently widely accepted in ophthalmology for retinal imaging purposes. In kidneys, the first experiments were performed on transplant kidneys to investigate the ability of OCT to assess ischaemic damage of kidneys. An ex vivo pilot study on the ability of OCT to differentiate normal renal tissue from malignant renal tissue, showed positive results and here we present the results of the first in vivo experiment. The study shows for the first time that in vivo OCT is feasible and safe to perform in humans and ...

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