1. Does neovascularization predict response to statin therapy? Optical coherence tomography study

    Does neovascularization predict response to statin therapy? Optical coherence tomography study

    Angiogenesis in atherosclerosis is reminiscent of angiogenesis in tumor . It is widely accepted that tumor neovascularization (NV) has a substantial influence on tumor response to cytotoxic therapies in a clinical setting . Likewise, it is possible that the presence of NV within atherosclerotic plaques can influence the effect of anti-atherosclerotic therapy on plaque stabilization or regression. We sought to determine whether NV within lesions could predict the anti-atherosclerotic effects of statin therapy as evaluated by optical coherence tomography (OCT).

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