1. Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: Impact of Signal Strength on Analysis of the RNFL Map

    Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: Impact of Signal Strength on Analysis of the RNFL Map
    Purpose: The objective of the study was to investigate the influence of signal strength (SS) on retinal nerve fiber layer (RNFL) measurement and interpretation of the RNFL thickness deviation map obtained with a spectral-domain optical coherence tomography. Design: Cross-sectional study. Methods: Thirty-seven eyes from 37 normal subjects were included. Six cube scans, each with 200 × 200 RNFL measurement pixels covering an area of 6 × 6 mm2 at the optic disc region with SS from 5 to 10, were collected with the Cirrus HD–optical coherence tomography (Carl Zeiss Meditec Inc, Dublin, Calif) by varying the level of polarization. The differences ...
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