High resolution Spectral Domain-OCT imaging in Geographic Atrophy associated with Age-related Macular Degeneration.
Purpose: To describe morphological variations in outer retinal layers in eyes with atrophic age-related macular degeneration (AMD) using high-resolution, spectral-domain optical coherence tomography (SD-OCT). Methods: SD-OCT scans were obtained with a combined confocal scanning laser ophthalmoscope (cSLO) and SD-OCT for simultaneous tomographic and topographic in vivo imaging. A total of 81 eyes of 56 patients (mean age 77.8 +/- 7.4) with geographic atrophy (GA) were examined. Morphological alterations were analyzed and classified in the perilesional zone, at the junction between GA and non atrophic retina, and in the atrophic area itself. Results: In the perilesional zone, distinct morphological alterations ...Read Full Article