1. Ex Vivo Assessment of Vascular Response to Coronary Stents by Optical Frequency Domain Imaging

    Ex Vivo Assessment of Vascular Response to Coronary Stents by Optical Frequency Domain Imaging

    Objectives This study sought to examine the capability of optical frequency domain imaging (OFDI) to characterize various morphological and histological responses to stents implanted in human coronary arteries. Background A precise assessment of vascular responses to stents may help stratify the risk of future adverse events in patients who have been treated with coronary stents. Methods Fourteen human stented coronary segments with implant duration ≥1 month from 10 hearts acquired at autopsy were interrogated ex vivo by OFDI and intravascular ultrasound (IVUS). Comparison with histology was assessed in 134 pairs of images where the endpoints were to investigate: 1) accuracy ...

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