1. 2-D Pattern of Nerve Fiber Bundles in Glaucoma Emerging from Spectral-Domain Optical Coherence Tomography

    2-D Pattern of Nerve Fiber Bundles in Glaucoma Emerging from Spectral-Domain Optical Coherence Tomography
    Purpose: To correlate the thicknesses of focal regions of the macular ganglion cell layer with those of the peripapillary nerve fiber layer using spectral-domain optical coherence tomography (SD-OCT) in glaucoma subjects. Methods: Macula and optic-nerve-head SD-OCT volumes were obtained in 57 eyes of 57 subjects with open-angle glaucoma or glaucoma suspicion. Using a custom automated computer algorithm, the thickness of 66 macular ganglion cell layer regions and the thickness of 12 peripapillary nerve fiber layer regions were measured from registered SD-OCT volumes. The mean thickness of each ganglion-cell-layer region was correlated to the mean thickness of each peripapillary-nerve-fiber-layer region across ...
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