1. Noninvasive functional imaging of the retina at cellular resolution

    Noninvasive functional imaging of the retina at cellular resolution
    Intrinsic optical signal imaging allows noninvasive identification of localized retinal neural dysfunction, promising early diagnosis of eye diseases. It is well established that many eye diseases, such as age-related macular degeneration, retinitis pigmentosa, glaucoma and diabetic retinopathy are associated with pathological changes in the retina in multiple cell classes. Different eye diseases affect different types of retinal cells, some of which occur in localized areas of the retina in the early stage of the disease. Accurate identification of retinal dysfunction at the local, cellular level is essential for early disease detection and reliable treatment evaluation. However, given the delicate structure ...
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