1. Intracoronary Imaging Modalities for Vulnerable Plaques

    Intracoronary Imaging Modalities for Vulnerable Plaques

    The concept of vulnerable plaque (VP) has been widely accepted as the primary cause of acute coronary syndrome (ACS) and sudden cardiac death. ACS is thought to result fromsudden disruption of a VP with subsequent occlusive thrombosis. VP typically consists of several components; a large necrotic core, thin fibrous cap, increase in macrophage activity,increase in vaso vasorum, and positive remodeling.In recent years, invasive or non-invasive diagnostic imaging modalities have beendeveloped for indentifying VP. VP has been recognized in various modalities not only byvisualization of cross sectional images by high-resolution imaging modalities, such as virtualhistology intravascular ultrasound (VH-IVUS), integrated ...

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