Quantification of Glucose Diffusion in Human Lung Tissues by Using Fourier Domain Optical Coherence Tomography
In this study, we report permeability coefficients of 30% glucose diffusion by the optical coherence tomography signal slope (OCTSS) method in four kind of human lung tissue in vitro: normal lung tissue, benign granulomatosis lung tissue, squamous cell carcinoma, and adenocarcinoma tumor. To quantify the permeability coefficient of the agent, the monitored region was the 80 um thickness at a tissue depth of approximately 230 um from the surface. The permeability coefficients of 30% glucose from 10 independent experiments were averaged and found to be (1.35 ± 0.13)×10 −5 cm/s from the normal lung tissue, (1.78 ...
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