1. Diurnal variation of choroidal thickness in normal, healthy subjects

    Diurnal variation of choroidal thickness in normal, healthy subjects
    Purpose: To describe the pattern and magnitude of diurnal variation of choroidal thickness (CT), its relation to systemic and ocular factors, and to determine the inter-visit reproducibility of diurnal patterns. Methods: A prospective study was conducted on 12 healthy volunteers who each underwent sequential ocular imaging on 2 separate days at 5 fixed, two-hourly time intervals. Spectral Domain Optical Coherence Tomography (OCT) with Enhanced Depth Imaging and image tracking was performed using a standardized protocol. Choroidal and retinal thicknesses were independently assessed by 2 masked graders. CT diurnal variation was assessed using repeated measures Analysis of Variance (ANOVA). Results: A ...
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