1. Optical coherence tomography for rapid tissue screening and directed histological sectioning

    Optical coherence tomography for rapid tissue screening and directed histological sectioning
    In pathology, histological examination of the tissue is the “gold standard” to diagnose various diseases. It has contributed significantly toward identifying the abnormalities in tissues and cells, but has inherent drawbacks when used for fast and accurate diagnosis. These limitations include the lack of in vivo observation in real time and sampling errors due to limited number and area coverage of tissue sections. Its diagnostic yield also varies depending on the ability of the physician and the effectiveness of any image guidance technique that may be used for tissue screening during excisional biopsy. In order to overcome these current limitations ...
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