Feature Of The Week 11/6/11: Nicolaus Copernicus University Researchers Develop Technique to Study Biomechanical Properties of The Cornea Using OCT
Researchers from Nicolaus Copernicus University have a long history of development of OCT in general and ophthalmology in particular. Recently NCU developed a technique to study the mechanical dynamics of the cornea using high speed OCT combined with an air puff system. Below is a summary of their work.
We present a novel method and instrument for in vivo imaging and measurement of the human corneal dynamics during an air puff. The instrument is based on high-speed swept source optical coherence tomography (ssOCT) combined with a custom adapted air puff chamber from a non-contact tonometer, which uses an air stream to deform the cornea in a non-invasive manner. During the short period of time that the deformation takes place, the ssOCT acquires multiple A-scans in time (M-scan) at the center of the air puff, allowing observation of the dynamics of the anterior and posterior corneal surfaces as well as the anterior lens surface. The dynamics of the measurement are driven by the biomechanical properties of the human eye as well as its intraocular pressure. Thus, the analysis of the M-scan may provide useful information about the biomechanical behavior of the anterior segment during the applanation caused by the air puff. An initial set of controlled clinical experiments are shown to comprehend the performance of the instrument and its potential applicability to further understand the eye biomechanics and intraocular pressure measurements. Limitations and possibilities of the new apparatus are discussed.
For more information see recent Article. Courtesy Maciej Wojtkowski and Karol Karnowski.