1. Determinants of Quantitative Optic Nerve Measurements using Spectral Domain Optical Coherence Tomography in a Population-based Sample of Non-glaucomatous Subjects

    Determinants of Quantitative Optic Nerve Measurements using Spectral Domain Optical Coherence Tomography in a Population-based Sample of Non-glaucomatous Subjects
    Purpose: To evaluate the ocular and systemic factors influencing measurements of optic nerve head (ONH) parameters and retinal nerve fiber layer (RNFL) thickness with spectral-domain optical coherence tomography (SD-OCT) in healthy Chinese adults. Methods: Adults aged 40 to 80 years were consecutively recruited from the population-based Singapore Chinese Eye Study. Cirrus high-definition OCT (Carl Zeiss Meditec Inc, Dublin, CA) was used to measure ONH and RNFL parameters. A total of 542 eyes from 542 non-glaucoma Chinese subjects were analyzed. Univariable and multiple linear regression analyses were performed to examine the effects of a range of ocular (e.g., intraocular pressure ...
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