1. Hypodense Regions (Holes) in the Retinal Nerve Fiber Layer in Frequency-Domain OCT Scans of Glaucoma Patients and Suspects

    Hypodense Regions (Holes) in the Retinal Nerve Fiber Layer in Frequency-Domain OCT Scans of Glaucoma Patients and Suspects
    Purpose. To better understand hypodense regions (holes) that appear in the retinal nerve fiber layer (RNFL) of frequency-domain optical coherence tomography (fdOCT) scans of patients with glaucoma and glaucoma suspects. Methods. Peripapillary circle (1.7-mm radius) and cube optic disc fdOCT scans were obtained on 208 eyes from 110 patients (57.4 ± 13.2 years) with glaucomatous optic neuropathy (GON) and 45 eyes of 45 controls (48.0 ± 12.6 years) with normal results of fundus examination. Holes in the RNFL were identified independently by two observers on the circle scans. Results. Holes were found in 33 (16%) eyes of ...
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