1. Dynamics of Human Foveal Development after Premature Birth

    Dynamics of Human Foveal Development after Premature Birth
    Purpose: To determine the dynamic morphologic development of the human fovea in vivo using portable spectral domain-optical coherence tomography (SD-OCT).Design: Prospective, observational case series.Paticipants: Thirty-one prematurely born neonates, 9 children, and 9 adults.Methods: Sixty-two neonates were enrolled in this study. After examination for retinopathy of prematurity (ROP), SD-OCT imaging was performed at the bedside in nonsedated infants aged 31 to 41 weeks postmenstrual age (PMA) (= gestational age in weeks + chronologic age) and at outpatient follow-up ophthalmic examinations. Thirty-one neonates met eligibility criteria. Nine children and nine adults without ocular pathology served as control groups. Semiautomatic retinal layer ...
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