The effects of race, optic disc area, age, and disease severity on the diagnostic performance of spectral domain optical coherence tomography.
Purpose: To evaluate the effect of race (African or European descent), age, disc area, and severity of disease on the diagnostic ability of spectral domain optical coherence tomography (SDOCT) imaging of the optic nerve, macula, and retinal nerve fiber layer (RNFL) in the detection of glaucomatous injury. Design: Cross-sectional observational study. Methods: Data from SDOCT images from 312 eyes from 167 subjects without ocular disease and 233 eyes from 163 patients with open angle glaucoma. Receiver operating characteristic (ROC) regression modeling technique was used to evaluate the influence of race on the diagnostic accuracies of the ONH, RNFL and macular ...Read Full Article