Feature Of The Week 6/5/11: Researchers from Toyohashi Heart Center Compare Multislice Computed Tomography and Optical Coherence Tomography for In-Vivo Assessment of Vulnerable Plaque
Cardiovascular disease is one of the major causes of death in the world. One component of this deadly disease is the rupture or thin walled unstable plaques. Increased detection of rupture-prone vulnerable plaque could be promising for better risk stratification of patients and lead to greatly improved cardiovascular care. Intravascular OCT has emerged as one of the most promising techniques for non-ionizing, high-resolution, in-vivo plaque characterization and assessment. However OCT is still an (minimally) invasive procedure. Multislice computed tomography (MSCT) has been proposed as a noninvasive imaging technique that can evaluate not only coronary artery stenosis but also detect and classify coronary plaque in vivo. However, the potential of MSCT to identify thin-capped fibroatheroma (TCFA) is controversial. Researchers from the Toyohashi Heart Center have been very active in OCT and in this study investigate the possibility of MSCT to detect TCFA derived by optical coherence tomographic imaging.
For more information see recent Article. Courtesy Tsuyoshi Ito.