1. Fourier-Domain OCT in multiple sclerosis patients: Reproducibility and ability to detect retinal nerve fiber layer atrophy

    Fourier-Domain OCT in multiple sclerosis patients: Reproducibility and ability to detect retinal nerve fiber layer atrophy
    PURPOSE: To evaluate the ability of Fourier-domain (FD) optical coherence tomography (OCT) to detect retinal nerve fiber layer (RNFL) atrophy in multiple sclerosis (MS) patients. To test the intra-session reproducibility of RNFL thickness measurements in MS and healthy subjects using Cirrus and Spectralis OCT. METHODS: Two hundred and twenty-two eyes of 111 subjects (50 MS patients and 61 healthy subjects) underwent three 360° circular scans centered on the optic disc by the same experienced examiner using the Cirrus and Spectralis OCT instruments. Differences between healthy and MS eyes were compared. The relationship between average thicknesses with each OCT was evaluated ...
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