1. Current Munich status concerning in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract

    Current Munich status concerning in-vivo optical coherence tomography for differentiating lesions of the upper aerodigestive tract
    Objective Non-invasive differentiation of pre- and early malignant mucosal changes may be helpful to reduce the morbidity and shorten the time to diagnosis for the patients concerned. Optical Coherence Tomography (OCT) seems to be well suited to reach this goal. Methods 61 patients with a total of 82 primary leukoplakic or erythroplakic mucosal lesions of the upper aerodigestive tract (OADT) were prospectively examined using an in-vivo, time-domain OCT (Niris®, Imalux Corporation, USA; lateral resolution 25 μm / axial resolution 15 μm) so far. The results were subsequently correlated to histopathology of tissue biopsies taken from the same areas. Additionally, intensity profiles ...
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