1. Temporal Macular Thinning on Spectral-Domain Optical Coherence Tomography in Proliferative Sickle Cell Retinopathy

    Temporal Macular Thinning on Spectral-Domain Optical Coherence Tomography in Proliferative Sickle Cell Retinopathy
    Sickle cell retinopathy is associated with retinal ischemia due to sickling of red blood cells in retinal arterioles that supply nutrients to the inner retinal layers.1-2 Proliferative sickle cell retinopathy (PSR) results in neovascularization caused by occlusion of the peripheral arteriole, typically at the branching points of the arterioles.3 Although neovascularization may be seen at the optic disc and the macula, PSR is primarily a peripheral ischemic retinal disease that results in vitreous hemorrhage and retinal detachment.1 However, peripheral ischemia can easily be missed on clinical examination, and invasive techniques such as wide-field angiography are required to ...
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