1. Visualisation of human subcutaneous blood vessels by increasing coherence probing depth

    Visualisation of human subcutaneous blood vessels by increasing coherence probing depth
    An improved Fourier-domain rapid-scanning optical delay in the reference arm of a Michelson interferometer is described which allows the use of a low-power superluminescent diode (down to 0.2 mW) and of a few wavelengths simultaneously. The method of raster scanning and averaging in the sample arm of the interferometer within a pixel provides an additional increase in the signal-to-noise ratio by 4–10 dB and, in combination with optical clearing, an increase in the coherence probing depth for the human skin in vivo up to 1.5–1.6 mm. As a result, subcutaneous blood vessels are visualised for ...
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