1. In-vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography

    In-vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography
    Purpose. To describe the in-vivo evolution of laser-induced choroidal neovascularization (CNV) in mice using spectral domain optical coherence tomography (SD-OCT) Methods. Laser photocoagulation was applied to the mouse fundus using a 532 nm diode-laser (100,150 and 200 mW, 100 μm diameter, 0.1 sec duration). SD-OCT examination was performed immediately after laser application, and at day 3, 5, 7, 14, 21 and 28 after laser. Fluorescein angiography (FA) was performed at day 5, 7, 14 and 28. Acquired SD-OCT images were analyzed to describe morphologic features, measure CNV size and retinal thickness, and assess the frequency of lesions resulting ...
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