1. Imaging Retinal Capillaries Using Ultrahigh-Resolution Optical Coherence Tomography and Adaptive Optics

    Imaging Retinal Capillaries Using Ultrahigh-Resolution Optical Coherence Tomography and Adaptive Optics
    Purpose: Ultrahigh-resolution optical coherence tomography (UHR-OCT) with adaptive optics (AO) provides micron-scale 3D resolution that is attractive for imaging the retinal microvasculature. Such imaging may be useful for early detection of pathologic changes as in diabetic retinopathy. Here we investigate this potential for detecting individual capillaries in healthy subjects. Methods: UHR-AO-OCT volumes centered on the fovea were acquired from seven subjects (25-61 years) with three pre-selected with no foveal avascular zone (FAZ). Images were compared to entoptic diagrams using the capillaries at the rim of the FAZ. Methods of comparison were: testing for the presence of a FAZ; noting distinct ...
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