1. Advanced Diagnostics in Renal Mass Using Optical Coherence Tomography: A Preliminary Report

    Advanced Diagnostics in Renal Mass Using Optical Coherence Tomography: A Preliminary Report
    Objective: To avoid unnecessary surgical treatment of small renal masses (≤4cm), a more accurate diagnostic method would be desirable since radiological differentiation between malignant and benign is difficult and nondiagnostic biopsies account from 9% to 37%. Optical coherence tomography (OCT) measures backscattered light versus depth, with an attenuation coefficient (μt) that may vary among different histological types. We hypothesize that quantitative measurements of μt using OCT can differentiate between normal renal parenchyma and renal cell carcinoma (RCC). Materials and Methods: Both normal and tumor renal tissues (RCC) were harvested after partial or radical nephrectomy. Analysis of μt was based on ...
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