1. Optical Coherence Tomography: 20 Years After

    Optical Coherence Tomography: 20 Years After
    Almost 20 years ago, in November 1991, the first description of optical coherence tomography (OCT) was published in the journal Science.1 The first clinical instrument was developed and studied at the New England Eye Center and Tufts University School of Medicine in Boston.2-7 It is conservatively estimated that more than 20,000 OCT systems are in use around the world. OCT initially revolutionized the diagnosis and treatment of macular disease, accelerated by the widespread use of intravitreally delivered drugs for the treatment of neovascular macular degeneration and diabetic macular edema. OCT-based quantitative assessment of the retinal nerve fiber ...
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