1. Path-Length-Resolved Diffusive Particle Dynamics in Spectral-Domain Optical Coherence Tomography

    Path-Length-Resolved Diffusive Particle Dynamics in Spectral-Domain Optical Coherence Tomography
    We describe a new method to measure the decorrelation rate of the optical coherence tomography (OCT) magnitude simultaneously in space and time.We measure the decorrelation rate of the OCT magnitude in a Fourier-domain OCT system for a large range of translational diffusion coefficients by varying the sphere diameter. The described method uses the sensitivity advantage of Fourier-domain OCT over time-domain OCT to increase the particle diffusion imaging speed by a factor of 200. By coherent gating, we reduce the contribution of multiple scattering to the detected signal, allowing a quantitative study of diffusive particle dynamics in high concentration samples ...
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