1. Decreased retinal nerve fiber layer thickness in patients with obstructive sleep apnea/hypopnea syndrome

    Decreased retinal nerve fiber layer thickness in patients with obstructive sleep apnea/hypopnea syndrome
    Background To compare parameters for retinal nerve fiber layer (RNFL) thickness, optic nerve head (ONH) measurements, and macular thickness in patients with different severities of obstructive sleep apnea/hypopnea syndrome (OSAHS) versus normal controls. Methods Patients presenting with snoring and daytime sleepiness who underwent overnight polysomnography to determine OSAHS severity were recruited, and subsequently referred for ophthalmologic evaluation. Optical coherence tomography was used to evaluate the retinal nerve fiber layer (RNFL), optic nerve head topography, and macular thickness for early detection of glaucoma. Patients determined not to have OSAHS were included as controls. Results A total of 127 subjects were ...
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