1. Optical coherence tomography of the larynx in the awake patient

    Objective To demonstrate the feasibility of performing optical coherence tomography of the human larynx on the awake patient with a novel flexible fiberoptic delivery system. Study Design Prospective clinical trial. Subjects and Methods Imaging was performed in 17 awake patients. A flexible optical coherence tomography probe was inserted through the nose and placed in near or gentle contact with laryngeal tissues under direct endoscopic visualization. Results Images were successfully obtained from all laryngeal subsites and clearly identified laryngeal mucosal microanatomy. Several critical probe design modifications improved rotational and angular control of the distal tip while allowing linear translation of the ...
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