1. Volumetric in vivo imaging of intracochlear microstructures in mice by high-speed spectral domain optical coherence tomography

    Volumetric in vivo imaging of intracochlear microstructures in mice by high-speed spectral domain optical coherence tomography
    There is considerable interest in developing new methods for in vivo imaging of the complex anatomy of the mammalian cochlea for clinical as well as fundamental studies. In this study, we explored, the feasibility of spectral domain optical coherence tomography (SD-OCT) for 3-D in vivo imaging of the cochlea in mice. The SD-OCT system employed in this study used a broadband light source centered at 1300 nm, and the imaging speed of the system was 47,000 A-scans per second using the InGaAs camera. The system was capable of providing fully processed, high-resolution B-scan images [512 (axial)×128 (lateral) pixels ...
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