Feature Of The Week 6/27/10: Progress Report on Building an Anatomically Correct Solid Eye Model with Volumetric Representation of Retinal Morphology
Feature Of The Week 6/27/10: The following summary is provided by T. Scott Rowe of Rowe Technical Design describing work on a reference eye model for OCT imaging.
I have long had an interest in seeing how OCT technology could better integrate into retinal ophthalmic practices. The improvements in axial resolution and overall image quality of these instruments, particularly in the past few years have been impressive! One element that, in my opinion, has been missing in the overall embrace of OCT technology has been the absence of a standard, well-characterized test “eye” (tissue phantom). If we look at other types of diagnostic instruments in ophthalmology, we note the presence of many types of test eyes being used in instrument comparisons and overall development. Examples include the corneal topographer1, the refractometer2, and even more recently, wavefront aberrometers have been well characterized by test eyes3. The need for a standard test eye within the OCT community is now becoming apparent as well. There have been comparisons of instruments done with a single cohort of patients, showing different retinal thickness results4. With substantial multi-center trials on-going in diabetic macular edema, it is more important than ever to know how instruments compare in critical RT measurements. In addition, a test eye can help in the on-going need to facilitate training of ophthalmic technicians in the accurate use of high resolution OCTs. Further, it can facilitate the development of new OCTs by engineers and the demonstration of OCTs by marketing and sales personnel. This attached progress report discusses our work in developing such a test eye for the ophthalmic community. It has certainly been a challenge to date! I welcome your comments and questions.
Rowe Technical Design, Inc.
1. See for example, Klein, S.A. “Corneal Topography: A review, new ANSI standards and problems to solve” OSA TOPS Vol. 35 Vision Science and its Applications pp. 286-296 (2000).
2. ISO 10342:2010 Ophthalmic Instruments – Eye refractometers
3. Campbell, C.E. “A Test Eye for Wavefront Eye Refractors” J. Refractive Surgery Vol. 21 pp. 127-140. (2005).
4. See for example, Grover, S., et.al. “Comparison of Retinal Thickness in Normal Eyes Using Stratus and Spectralis Optical Coherence Tomography” Investigative Ophthalmology and Visual Science, May 2010, Vol. 51, No.5 pp. 2644-2647.