1. Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

    Quantitative Assessment of Diffuse Retinal Nerve Fiber Layer Atrophy Using Optical Coherence Tomography: Diffuse Atrophy Imaging Study

    Purpose: To evaluate quantitatively the degree of diffuse retinal nerve fiber layer (RNFL) atrophy using Stratus optical coherence tomography (OCT).Design: Prospective, cross-sectional study.Participants: One hundred two eyes of 102 patients with diffuse RNFL atrophy and 102 healthy eyes of 102 age-matched subjects were enrolled in the Diffuse Atrophy Imaging Study.Methods: Two experienced observers graded RNFL photographs of diffuse RNFL atrophy eyes using a previously reported standardized protocol with a 4-level grading system. Readings were taken from the superior and inferior RNFL areas. The OCT-measured RNFL thickness parameters were compared among normal eyes and diffuse atrophy subgroups. Area ...

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