1. In vitro study of ultrasound and different-concentration glycerolinduced changes in human skin optical attenuation assessed with optical coherence tomography

    In vitro study of ultrasound and different-concentration glycerolinduced changes in human skin optical attenuation assessed with optical coherence tomography

    Previous studies have demonstrated the ultrasound-induced skin optical clearing enhancement with topical application of 60% glycerol (G) on in vitro porcine skin and in vivo human skin. Our purpose was to find the relation between the effect of optical skin clearing and different concentrations of glycerol and to find more effective ultrasound-glycerol combinations on optical skin clearing. The enhancement effect of ultrasound [Sonophoresis (SP) delivery] in combination with 40% G, 60% G, and 80% G on in vitro human skin optical clearing was investigated. Light imaging depths of skin were measured using optical coherence tomography. Different concentrations of glycerol and ...

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