1. Optical Coherence Tomography as an Adjunct to Flexible Bronchoscopy in the Diagnosis of Lung Cancer: A Pilot Study

    Optical Coherence Tomography as an Adjunct to Flexible Bronchoscopy in the Diagnosis of Lung Cancer: A Pilot Study
    Background: Lung cancer is the leading cause of cancer-related deaths in the United States and the second most common type of cancer in both men and women. Optical coherence tomography (OCT) can generate high resolution cross-sectional images of complex, living tissues in real time. The objectives of this study were to determine the feasibility of using OCT during flexible bronchoscopy, and to preliminarily assess the ability of OCT to distinguish an endobronchial malignancy from normal endobronchial mucosa. Methods: A NirisTM OCT probe was introduced into the airways of patients with an endobronchial mass during flexible bronchoscopy. An investigational device exemption ...
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