1. University of Iowa to Study Macular Degeneration - Lands $2.8M NEI Grant

    University of Iowa to Study Macular Degeneration - Lands $2.8M NEI Grant
    An interdisciplinary team of scientists at the University of Iowa has been awarded a five-year, $2.8 million grant from the National Eye Institute (NEI) to improve how doctors manage treatment for patients with the wet form of age-related macular degeneration (AMD). The study will examine how advanced imaging -- known as three-dimensional optical coherence tomography -- and related image analysis can be used to assess changes in the macula and retina of patients' eyes. These changes can reveal how well a person is responding to anti-VEGF treatment and thus help doctors provide proper treatment timing and care.
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    1. Effective treatments involving injections into the eye have recently become available to restore vision for people with the wet form of AMD...These treatments have benefits, but they are costly and the risk of serious side effects to the eye increases with repeated injections. Our study goal is to learn how to tailor dosing for each patient so that the minimal necessary number of injections is used.
    2. We have learned a great deal by working with UI cardiologists and radiologists about how to manage three-dimensional data...We can now apply this experience efficiently to other areas, including ophthalmology. The physicians cannot do their work without the engineers, and the engineers cannot do their work without the physicians. It's an important collaboration that makes research possible. We hope this study will bring improved image-guided treatment of the most prevalent cause of blindness in the United States.
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