1. Detection of Cystoid Macular Edema with Three-Dimensional Optical Coherence Tomography versus Fluorescein Angiography

    Purpose: To compare the sensitivity and reproducibility of three-dimensional optical coherence tomography (3D-OCT) and fluorescein angiography (FA) for the detection of cystoid macular edema (CME). Methods: Data from all patients who underwent digital FA (Topcon 50IX, Topcon Corp.) and 512x128 horizontal raster 3D-OCT scans (3D-OCT-1000, Topcon Corp.) on the same day in a retina subspecialty clinic were retrospectively collected. Images were reviewed independently by four reading center graders and adjudicated as a group to render a single result for each eye and each imaging modality. Kappa statistics were used to determine the level of agreement between graders for each modality ...

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