Identification and Assessment of Schlemm's Canal by Spectral Domain Optical Coherence Tomography
Purpose: Measurements of human Schlemm's canal (SC) have been limited to histological sections. The purpose of this study was to demonstrate non-invasive measurements of aqueous outflow (AO) structures in the human eye, examining regional variation in cross-sectional SC areas (on/off collector channel (CC) ostia (SC/CC), and nasal/temporal) in the eyes of living humans.
Methods: SC was imaged by spectral-domain optical coherence tomography (SD-OCT, Bioptigen Inc, USA) with a 200 nm bandwidth light source (SuperLum LTD., Ireland). Both eyes of 21 healthy subjects and 1 glaucomatous eye of 3 subjects were imaged nasally and temporally. Contrast and ...
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