1. Real-time intraoperative spectral domain optical coherence tomography for vitreoretinal surgery

    Real-time intraoperative spectral domain optical coherence tomography for vitreoretinal surgery
    Vitreoretinal surgery visualization is inherently limited by the ability to distinguish between tissues with subtle contrast, and to judge the location of an object relative to other retinal substructures. Inherent issues in visualizing thin translucent tissues, in contrast to underlying semitransparent ones, require the use of stains such as indocyanine green, which is toxic to retinal tissue. Spectral domain optical coherence tomography (SDOCT) has demonstrated strong clinical success in retinal imaging, enabling high-resolution, motion-artifact-free cross-sectional imaging and rapid accumulation of volumetric macular datasets. Current generation SDOCT systems achieve <5 µm axial resolutions in tissue, and have been used to obtain ...
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