1. High Resolution Fourier-Domain Optical Coherence Tomography of Choroidal Neovascular Membranes Associated with Age-Related Macular Degeneration

    Purpose: To investigate to use of high resolution Fourier-domain optical coherence tomography (Fd-OCT) to image choroidal neovascular membranes (CNVM) associated with exudative age-related macular degeneration (eAMD). Methods: An Fd-OCT instrument with axial resolution of 4 to 4.5 µm and transverse resolution of 10 to 15 µm was used to image 21 eyes (19 subjects) with newly-diagnosed eAMD. A raster series of 100 B-scans separated by 60 µm was used study the growth pattern of CNVM and associated morphologic changes. CNVM size was determined using 250 to 300 serial virtual C-scans of reconstructed 3-dimensional macular volume. Results: A highly reflective ...
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